Accutan
Description:
Accutane is a
powerful drug used in the treatment of acne. Four to five months of
isotretinoin treatment usually leads to clearing of acne for one year or
more after the medicine is stopped. Most other acne-controlling
medicines are antibacterial agents, which are effective only if the
medicine is used daily.Isotretinoin has significant side effects:
(percentages are the ratio of people who received the side-effect)
Chapped lips 90% , dry skin and itching 80% - the use of daily alpha
hydroxacids will help prevent this side effect. Dryness of nose, mild
nosebleed 80%, Irritation of the eyelids and eyes 40% - Vitamin E 400 IU
each day may lessen this side effect. Joint and muscle pains 15%,
Temporary hair thinning 10%, Rash 7%, Intestinal symptoms 5%, Urinary
symptoms 5%, Headache 5%, Increased sensitivity to sunburn 5%, Decreased
night vision <1%, Depression, thoughts of suicide <1%
Isotretinoin may increase the level of blood fats, sometimes to risky
levels. Occasionally it may affect the liver. That's why regular blood
tests are necessary when you are taking isotretinoin; these tests must
be done when you have fasted for 12 hours (no breakfast), so that the
blood fat determinations are reliable. A baseline blood chemistry test
is established before patients start isotretinoin.
The most damaging side effect of isotretinoin is serious birth defects
if taken during pregnancy.
It is critically important for women not to take isotretinoin while
pregnant, and not to become pregnant while taking it. Women who are, or
expect to be, sexually active while taking isotretinoin must use an
effective method of birth control. This usually means oral contraceptive
pills and one other additional method of birth control such as a condoms
for the male partner. A woman who does get pregnant while on
isotretinoin must be prepared to have an abortion and must state this in
writing before many hysicians will prescribe isotretinoin for
her.Isotretinoin may cause birth defects as long as two months after it
is stopped. After that time, it's safe to become pregnant. Because the
birth defects caused by isotretinoin are so serious, it's important not
to share the pills with others.We don't know whether isotretinoin taken
by men can cause birth defects, so it's best not to get a woman pregnant
while taking isotretinoin. If she is not using birth control, the man
should use a condom.There are a few reports of patients having decreased
night vision after using Accutane. One patient still had problems six
months after the drug was stopped. If you experience trouble with your
vision while on Accutane, call the office right away.
Some people
develop headaches while on Accutane. If you develop a persistent
headache while on Accutane, call your physician right away. A persistent
headache, which will not go away while on Accutane, can be dangerous and
you should stop the medication.
Accutane rarely causes depression and thoughts of suicide. If this were
to occur stop the medicine immediately and call your physician.
How does isotretinoin work?Isotretinoin decreases the amount of oil
produced by the skin's sebaceous (oil) glands. It may be as long as two
months before you see improvement in your skin. There's no medicine we
can add to speed up isotretinoin's action. In fact, sometimes acne gets
worse during the first month or so of treatment. Side effects, such as
lip dryness, begin before the acne starts to clear.
How To Use Isotretinoin:Take the medicine with food, you can take the
entire daily dose with supper, this increases the absorption of the
medicine.
Long-term Results:Isotretinoin isn't a permanent cure for acne, although
it often buys time until nature clears your skin. Your skin may stay
clear for months, even years, after isotretinoin is stopped. In about
one person in 10, acne comes back after one year. About one person in
four has acne again after two years. If your acne returns, antibiotics
may work, or you may be treated with isotretinoin again. The use of
daily alpha hydroxyacids will help prevent small flare-ups after a
course of Accutane.Unblocking the openings of the sebaceous glands
Accutane also suppresses the production of skin cells which block the
openings to the sebaceous glands. As a result, the quantity of
comedones, or blackheads, and milia, or whiteheads, is reduced. A
decrease in comedones in turn causes a decrease in the development of
suppurations, or pus-filled acne pimples, whose formation we seek to
prevent.
Anti-inflammatory activity It has been found that Accutane decreases
inflammation in laboratory trials, yet the clinical significance of this
discovery remains unclear.
Accutane's side effects Accutane is particularly effective in mid-range severity cases of acne, which have not responded to treatments such as ointments or oral antibiotics. The most significant risk in taking Accutane is its potential for causing birth defects in the developing fetus of a pregnant acne patient. Because of this risk, female patients should take care not to conceive while using Accutane and for at least three months following the end of treatment.
How to get the most out of Accutane??
Attention female patients !!! Accutane has been proven to cause birth defects in developing fetuses. Due to this danger, it is absolutely prohibited to conceive during Roaccutane treatment and for at least three months thereafter. All female users of Accutane should use two birth control methods during this entire period.
All patients: All Accutane users should expect mild chapping of the lips, and occasionally peeling of the skin surrounding the fingernails. The chapping and / or peeling will disappear by the end of the treatment. Relief from dry skin is available in the form of creams which the doctor will provide. In rare cases, dryness of the nose, slight hair loss, or impaired night vision is experienced, all of which disappear by the end of treatment. In still rarer cases, a change in liver function, an increase in fat production, or mood changes can occur. Inform your doctor of any kidney or liver disorders, high fat content in the blood, or depression in your family or medical history. A blood count should be performed before starting treatment, as well as once a month during treatment. The doctor should also be informed of any inordinate physical exertion undergone by the patient during Accutane treatment. Avoid taking any vitamin supplements, as well as over-exposure to the sun, while taking Accutane.
Package:
30 tablets per box. 10 mg per tablet.
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